Trajectory outlier detection: Algorithms, taxonomies, evaluation, and open challenges

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Identification and Assessment of Hadith in The Commentary of the Fi ZilâLi'l-Qur'an (Sura Fatiha; Bakara; Al̂ -i ImrâN)

Yüksek Lisans TeziÇalışmamızda, 20. asrın büyük dava ve ilim adamlarından olan Seyyid Kutub’un Fî Zılâli’l-Kur’ân adlı eserinin Fatiha, Bakara ve Âl-i İmrân Sûrelerinin tefsirinde geçen hadislerin tahrîc ve değerlendirmesini yaparak bu tefsirinde geçen rivayetlerin, hadis ilmi açısından güvenilirliğini ortaya koymaya çalıştık. Çalışmamız giriş ve iki bölümden oluşmaktadır. Giriş bölümünde araştırmanın konusu ve problemi, amacı, önemi ve araştırmanın yöntemi ile ilgili bilgiler verilmiştir. Birinci bölümde Seyyid Kutub’un hayatı, ilmi kişiliği, eserleri ve vefatı hakkında anlatılmaya çalışılmıştır. İkinci bölümde Seyyid Kutub’un Fî Zılâli'l Kur’ân adlı eserindeki (Fatiha, Bakara ve Âl-i İmrân Sûreleri)’nin tefsirinde geçen hadisler tespit edilip tahrîcleri yapmaya çalışılmış ve sıhhat durumuna göre sınıflandırma yapıp genel bir değerlendirme yapılmıştır.In our study, we tried to analyze identification and assesment of hadith in the Fi Zilali’l Qur’án (Sura Fatiha, Baqara and Al-Imran), which is written by one of the great scholars of the 20th century Seyyid Qutub and at the same time we tried toverify the reliability about these hadiths in this commentary according sciences ofhadiths. Our study consists on an introduction and two sections. In the introduction, are given about the purpose of the study and it’s important, problem of the research, the research method. In the first chapter, Sayyid Qutub's biography, his education and his works, In the second chapter, identification and assesment of hadith in the Fi Zilali’l Qur’án (Sura Fatiha, Baqara and Al-Imran) and classification along with general assessment according hadith’s terms and status

Droplet-based µChopper device with a 3D-printed pneumatic valving layer and a simple photometer for absorbance based fructosamine quantification in human serum

The development of microfluidic systems for biological assays presents challenges, particularly in adapting traditional optical absorbance assays to smaller volumes or to microfluidic formats. This often requires assay modification or translation to a fluorescence version, which can be impractical. To address this issue, our group has developed the µChopper device, which uses microfluidic droplet formation as a surrogate for an optical beam chopper, allowing for lock-in analysis and improved limits of detection with both absorbance and fluorescence optics without modifying the optical path length. Here, we have adapted the µChopper to low-cost optics using a light-emitting diode (LED) source and photodiode detector, and we have fabricated the pnuematically valved devices entirely by 3D printing instead of traditional photolithography. Using a hybrid device structure, fluidic channels were made in polydimethylsiloxane (PDMS) by moulding onto a 3D-printed master then bonding to a prefabricated thin layer, and the pneumatic layer was directly made of 3D-printed resin. This hybrid structure allowed an optical slit to be fabricated directly under fluidic channels, with the LED interfaced closely above the channel. Vacuum-operated, normally closed valves provided precise temporal control of droplet formation from 0.6 to 2.0 Hz. The system was validated against the standard plate reader format using a colorimetric fructosamine assay and by quantifying fructosamine in human serum from normal and diabetic patients, where strong correlation was shown. Showing a standard benefit of microfluidics in analysis, the device required 6.4-fold less serum volume for each assay. This µChopper device and lower cost optical system should be applicable to various absorbance based assays in low volumes, and the reliance on inexpensive 3D printers makes it more accessible to users without cleanroom facilities

Plasma B-Type Natriuretic Peptide (BNP) As a Marker of Left Ventricular Diastolic Dysfunction in Diabetic Patients

The first stage of diabetic cardiomyopathy is represented by left ventricular diastolic dysfunction (LVDD) with preserved systolic function, in an asymptomatic patient. B-type Natriuretic Peptide (BNP) is a cardiac neurohormone predominantly released from the cardiac ventricles in response to left ventricular volume expansion and pressure overload. The diagnostic role of BNP for detecting LVDD in asymptomatic diabetic patients is still debated and this study was undertaken to find out this relationship of plasma BNP level with LVDD in asymptomatic diabetic patients. First 100 patients who had type 2 diabetes for more than 5 years and had no known cardiac disease other than LVDD (grade-1 & 2), admitted in BIRDEM Hospital were recruited. Plasma BNP was measured by fluorescence polarization immunoassay (FPIA) method using AXSYM auto analyzer. Two-dimensional, M-mode, spectral, and color flow Doppler echocardiograms was repeated on the same day of blood collection for plasma BNP measurement. After processing of all available data, statistical analysis of their significance was done with the help of computer based SPSS (Statistical Program for Social Science) program. Male female distribution of the study participants was 46% and 54% respectively. Mean plasma BNP level in all participants was 150 pg/ml. In male and female participants the values were 168 and 135 pg/ml respectively. The distribution did not show any significant association (p=0.491). Of the 100 study participants 89% had E/A ratio <1. Distribution of participants with abnormal E/A and E/e did not show any significant association (p=0.955 and 0.844 respectively). Study participants with varying level of plasma BNP level were analyzed in terms of E/A and E/e ratio. Distribution of participants between BNP Groups and E/A and E/e groups did not show statistically significant association (p=0.529). We concluded that plasma BNP has no relation with LVDD (grade-1 and 2) in patients with type 2 diabetes mellitus (T2DM) who had no known cardiac disease. Ibrahim Med. Coll. J. 2014; 8(1): 1-

Childhood giant omental and mesenteric lipoma

Omental and mesenteric lipomas are very rare benign lesions of mature adipose tissue. They are well-defined, noninvasive, and encapsulated masses that can be discovered in asymptomatic patients or may cause variable nonspecific symptoms depending on their size and location. The omental and mesenteric lipoma has confusing features in ultrasound; however, computed tomography and magnetic resonance imaging can well characterize and demarcate these lesions. Though few cases of mesenteric and omental lipomas have been reported in the literature, but because of its large size and childhood presentation, the case we present, can be one of the largest childhood omental and mesenteric lipomas ever reported. A 6-year-old girl presented with slowly progressing abdominal distension and repeated dull abdominal pain for last 4 years. Abdominal and pelvic computed tomography examination revealed a huge mesenteric and omental lipoma that was resected surgically without any complications